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2025 Cannondale

Synapse LAB71 Frameset

A carbon frame endurance frameset.

Manufacturer Price

$5,999
FrameCarbon
ForkCarbon
Wheels700c
View on cannondale.comLearn about Cannondale
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Insights
Sizing
48cm

5'2" – 5'6"

51cm

5'5" – 5'10"

54cm

5'7" – 5'11"

56cm

5'9" – 6'1"

58cm

6'0" – 6'4"

61cm

6'3" – 6'8"

Rider Fit Notes
  • 6'2", size 56, Just right
  • 6'1", size 56, Just right
Price History
Reviews

Summary

The Cannondale Synapse is celebrated for its blend of performance and comfort, making it a standout in the endurance category. Its lightweight frame, advanced aerodynamics, and innovative features like the SmartSense system and StashPort storage highlight its versatility. The bike's design focuses on real-world performance, offering a smooth ride with improved compliance and handling.

Pros
  • Versatile and capable with real-world performance

  • Lightweight frames and advanced aerodynamics

  • Innovative features like SmartSense and StashPort

  • Improved comfort and stability with size-specific geometry

  • Wide tire clearance for versatility

Cons
  • SmartSense system compatibility questions with AXS derailleurs

  • Tire clearance limitations with certain setups

  • Added weight from SmartSense system

Key Quotes
The Cannondale Synapse is what happens when you take performance seriously—but not so seriously that you forget to smile during a five-hour ride.
Bikerumor logoBikerumor
"The Synapse now has drag figures that are basically on par with the previous third-generation SuperSix Evo, which, from all of our testing, would be an extremely competitive bike if it was still in the pro peloton," says Nathan Barry, Cannondale’s senior design engineer.
Canadian Cycling Magazine logoCanadian Cycling Magazine
The Synapse goes further than the other two bikes to prepare you for longer rides.
Cyclist logoCyclist

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View all reviews

Cycling News
Cannondale Synapse Carbon 2 review: Dependable and sure footed, but not as exciting to ride as some of the best endurance bikes on the market

Mar 2026

The 6th gen Synapse can handle a lot, but if you're looking for a more comfortable endurance bike, you will need to decide if its geometry and ride feel are for you

Highs
  • Confidence inspiring, sure footed handling

  • Comfortable geometry

  • Progressive tyre clearances mean you can do a lot with the bike

  • A good looking bike overall

Lows
  • Middle spec, tube-only tyres on a 6k bike is a let down

  • No alternate inline seatpost option for all sizes

  • Lacks a little bit of race bike excitement

Read Review

Road Bike Action
First Rides - Cannondale Synapse Carbon 2 with SmartSense - Road Bike Action

Mar 2026 · Joe Mackey

The Synapse has arguably been the most versatile bike in Cannondale’s lineup for the last several years. From the Cobbles in the Pro Tour to your favorite local Fondo, the Synapse has been ridden just about everywhere.  As a former owner of a Synapse, I can attest to the versatility of generations past. But this […]

Highs
  • Versatile geometry updates

  • Increased tire clearance (fork clears 48mm, rear clears 42mm)

  • Added aero features

  • Integrated SmartSense system with headlight and Garmin rear radar

  • Downtube storage

  • Smooth ride quality with 32mm Vittoria Rubino tires

  • Slightly more aggressive and racier geometry than previous Synapse

Lows
  • No power meter at $7500 price point

  • Slightly more aggressive geometry may not suit all endurance riders

Read Review

Gran Fondo Magazine
New Cannondale Synapse LAB71 SmartSense on Test – Is This Really the Future of All-Road Riding?

Nov 2025 · Calvin Zajac

With the Synapse LAB71 SmartSense, Cannondale present their vision of the future of all-road riding – but is the bike really worth its hefty price tag?

Highs
  • Versatile and fun handling

  • Vively ride feel

  • Extremely adaptable

  • Clean integration of lighting and electronics

Lows
  • Expensive

Read Review

Bicycling
The Cannondale Synapse Sets a New Standard for Endurance Road Bikes

Jul 2025

The Synapse forgoes comfort gimmicks in favor of ample tire clearance, solid geometry, and clean integration to deliver an exceptional riding experience.

Read Review

BikeRadar
Cannondale Synapse Lab71 review: the smartest new bike of 2025, but I could only afford a far cheaper option | BikeRadar

Jul 2025 · Warren Rossiter

The new Synapse Lab71 achieves something quite brilliant. It’s a fast and fun bike, yet also supremely comfortable both in its ride position and road chatter-smoothing character.

Highs
  • Flawless specification

  • Wonderful on road manners

  • Clever integration of smart sense

  • 1x drivetrain

Lows
  • Doesn t come cheap

Read Review

road.cc
Cannondale Synapse Carbon 4

Jun 2025

A belter of a bike with a price tag to match

Highs
  • Balanced geometry

  • Down tube storage

  • Electronic shifting

  • Well-considered cockpit

  • Great pricing

Lows
  • Heavy aluminium wheels

Read Review

Cyclist
New Cannondale Synapse vs Specialized Roubaix vs Trek Domane: Which is the best endurance road bike?

May 2025 · Paul Norman

Road bikes have for a long time been divided into two categories: race bikes and endurance bikes. While the former

Read Review

Bikerumor
Cannondale Synapse Can Run Your Electronics from One Battery and Has Room For Snacks

May 2025 · Jordan Villella

The Synapse was never the average endurance bike, the newest models reflect a refined road bike that wants to go fast, comfortably.

Read Review

Geometry
Specs
Build
Frame

LAB71 Synapse Hi-MOD Carbon, Proportional Response construction, integrated cable routing, downtube Stashport, 12x142 thru-axle, UDH, BSA 68mm threaded BB, flat mount disc, integrated seat binder, fender mounts

BB StandardBSA, 68mm, Threaded

Hanger StandardUDH

Tire Clearance48c

ColorBlack Marble

Fork

Lab71 Synapse Hi-MOD Carbon, integrated crown race, 12x100mm thru-axle, flat mount disc, internal routing, 1-1/8" to 1-1/5" Delta steerer, 55mm offset, fender mounts

Bottom Bracket

BSA, 68mm, threaded

Headset

Integrated, 1-1/8" - 1-1/2", w/ integrated spacers

Seatpost

Cannondale C1 Aero 27 Carbon, SmartSense compatible, 330mm length, 0mm offset (44-48cm), 15mm offset (51-61cm)

TypeRigid

Rider Notes
Riders Also Viewed

First added May 6

Last updated June 4