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Today’s DealsSynapse LAB71 Frameset
A carbon frame endurance frameset.
5'2" – 5'6"
5'5" – 5'10"
5'7" – 5'11"
5'9" – 6'1"
6'0" – 6'4"
6'3" – 6'8"
Summary
The Cannondale Synapse is celebrated for its blend of performance and comfort, making it a standout in the endurance category. Its lightweight frame, advanced aerodynamics, and innovative features like the SmartSense system and StashPort storage highlight its versatility. The bike's design focuses on real-world performance, offering a smooth ride with improved compliance and handling.
Versatile and capable with real-world performance
Lightweight frames and advanced aerodynamics
Innovative features like SmartSense and StashPort
Improved comfort and stability with size-specific geometry
Wide tire clearance for versatility
SmartSense system compatibility questions with AXS derailleurs
Tire clearance limitations with certain setups
Added weight from SmartSense system
The Cannondale Synapse is what happens when you take performance seriously—but not so seriously that you forget to smile during a five-hour ride.
"The Synapse now has drag figures that are basically on par with the previous third-generation SuperSix Evo, which, from all of our testing, would be an extremely competitive bike if it was still in the pro peloton," says Nathan Barry, Cannondale’s senior design engineer.
The Synapse goes further than the other two bikes to prepare you for longer rides.
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Mar 2026
The 6th gen Synapse can handle a lot, but if you're looking for a more comfortable endurance bike, you will need to decide if its geometry and ride feel are for you
Confidence inspiring, sure footed handling
Comfortable geometry
Progressive tyre clearances mean you can do a lot with the bike
A good looking bike overall
Middle spec, tube-only tyres on a 6k bike is a let down
No alternate inline seatpost option for all sizes
Lacks a little bit of race bike excitement

Mar 2026 · Joe Mackey
The Synapse has arguably been the most versatile bike in Cannondale’s lineup for the last several years. From the Cobbles in the Pro Tour to your favorite local Fondo, the Synapse has been ridden just about everywhere. As a former owner of a Synapse, I can attest to the versatility of generations past. But this […]
Versatile geometry updates
Increased tire clearance (fork clears 48mm, rear clears 42mm)
Added aero features
Integrated SmartSense system with headlight and Garmin rear radar
Downtube storage
Smooth ride quality with 32mm Vittoria Rubino tires
Slightly more aggressive and racier geometry than previous Synapse
No power meter at $7500 price point
Slightly more aggressive geometry may not suit all endurance riders

Nov 2025 · Calvin Zajac
With the Synapse LAB71 SmartSense, Cannondale present their vision of the future of all-road riding – but is the bike really worth its hefty price tag?
Versatile and fun handling
Vively ride feel
Extremely adaptable
Clean integration of lighting and electronics
Expensive

Jul 2025
The Synapse forgoes comfort gimmicks in favor of ample tire clearance, solid geometry, and clean integration to deliver an exceptional riding experience.

Jul 2025 · Warren Rossiter
The new Synapse Lab71 achieves something quite brilliant. It’s a fast and fun bike, yet also supremely comfortable both in its ride position and road chatter-smoothing character.
Flawless specification
Wonderful on road manners
Clever integration of smart sense
1x drivetrain
Doesn t come cheap

Jun 2025
A belter of a bike with a price tag to match
Balanced geometry
Down tube storage
Electronic shifting
Well-considered cockpit
Great pricing
Heavy aluminium wheels

May 2025 · Paul Norman
Road bikes have for a long time been divided into two categories: race bikes and endurance bikes. While the former

May 2025 · Jordan Villella
The Synapse was never the average endurance bike, the newest models reflect a refined road bike that wants to go fast, comfortably.
| Frame | LAB71 Synapse Hi-MOD Carbon, Proportional Response construction, integrated cable routing, downtube Stashport, 12x142 thru-axle, UDH, BSA 68mm threaded BB, flat mount disc, integrated seat binder, fender mounts BB Standard: BSA, 68mm, Threaded Hanger Standard: UDH Tire Clearance: 48c Color: Black Marble |
|---|---|
| Fork | Lab71 Synapse Hi-MOD Carbon, integrated crown race, 12x100mm thru-axle, flat mount disc, internal routing, 1-1/8" to 1-1/5" Delta steerer, 55mm offset, fender mounts |
| Bottom Bracket | BSA, 68mm, threaded |
| Headset | Integrated, 1-1/8" - 1-1/2", w/ integrated spacers |
| Seatpost | Cannondale C1 Aero 27 Carbon, SmartSense compatible, 330mm length, 0mm offset (44-48cm), 15mm offset (51-61cm) Type: Rigid |
First added May 6
Last updated June 4