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Today’s DealsSynapse Carbon 4
A carbon frame endurance bike with upper mid-range components and shimano 105 hydraulic disc brakes.
Manufacturer Price
$4,199| Frame | Carbon |
|---|---|
| Fork | Carbon |
| Wheels | 700c Aluminum |
| Drivetrain | 2 × 12 Electronic |
| Groupset | 105 Di2 |
| Brakes | Shimano 105 Hydraulic Disc |
5'0" – 5'5"
5'2" – 5'6"
5'5" – 5'10"
5'7" – 5'11"
5'9" – 6'1"
6'0" – 6'4"
6'3" – 6'8"
Summary
The Cannondale Synapse is celebrated for its blend of performance and comfort, making it a standout in the endurance category. Its lightweight frame, advanced aerodynamics, and innovative features like the SmartSense system and StashPort storage highlight its versatility. The bike's design focuses on real-world performance, offering a smooth ride with improved compliance and handling.
Versatile and capable with real-world performance
Lightweight frames and advanced aerodynamics
Innovative features like SmartSense and StashPort
Improved comfort and stability with size-specific geometry
Wide tire clearance for versatility
SmartSense system compatibility questions with AXS derailleurs
Tire clearance limitations with certain setups
Added weight from SmartSense system
The Cannondale Synapse is what happens when you take performance seriously—but not so seriously that you forget to smile during a five-hour ride.
"The Synapse now has drag figures that are basically on par with the previous third-generation SuperSix Evo, which, from all of our testing, would be an extremely competitive bike if it was still in the pro peloton," says Nathan Barry, Cannondale’s senior design engineer.
The Synapse goes further than the other two bikes to prepare you for longer rides.
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Mar 2026
The 6th gen Synapse can handle a lot, but if you're looking for a more comfortable endurance bike, you will need to decide if its geometry and ride feel are for you
Confidence inspiring, sure footed handling
Comfortable geometry
Progressive tyre clearances mean you can do a lot with the bike
A good looking bike overall
Middle spec, tube-only tyres on a 6k bike is a let down
No alternate inline seatpost option for all sizes
Lacks a little bit of race bike excitement

Mar 2026 · Joe Mackey
The Synapse has arguably been the most versatile bike in Cannondale’s lineup for the last several years. From the Cobbles in the Pro Tour to your favorite local Fondo, the Synapse has been ridden just about everywhere. As a former owner of a Synapse, I can attest to the versatility of generations past. But this […]
Versatile bike, suitable for various riding scenarios
Updated geometry: longer reach, shorter stack for racier feel
Increased tire clearance (48mm fork, 42mm rear)
Added aero features
Integrated SmartSense system with headlight and Garmin rear radar
Downtube storage for battery, tool kit, etc.
Smooth ride quality with stock 32mm Vittoria Rubino tires
No power meter included at $7500 price point
SmartSense system may be unnecessary for some riders

Nov 2025 · Calvin Zajac
With the Synapse LAB71 SmartSense, Cannondale present their vision of the future of all-road riding – but is the bike really worth its hefty price tag?
Versatile and fun handling
Vively ride feel
Extremely adaptable
Clean integration of lighting and electronics
Expensive

Jul 2025
The Synapse forgoes comfort gimmicks in favor of ample tire clearance, solid geometry, and clean integration to deliver an exceptional riding experience.

Jun 2025
A belter of a bike with a price tag to match
Balanced geometry
Down tube storage
Electronic shifting
Well-considered cockpit
Great pricing
Heavy aluminium wheels

May 2025 · Jordan Villella
The Synapse was never the average endurance bike, the newest models reflect a refined road bike that wants to go fast, comfortably.

May 2025 · Matthew Pioro
The latest bike not only has features that will make you speedier, it will get you out on the roads faster New Cannondale Synapse: Expanded endurance-bike technology
May 2025 · Alvin Holbrook
Remember that clunky SmartSense system? Its back and wrapped around one of the most compelling road bikes of 2025, the Cannondale Synapse.
| Frame | Synapse Carbon, Proportional Response construction, integrated cable routing, downtube Stashport, 12x142 thru-axle, UDH, BSA 68mm threaded BB, flat mount disc, integrated seat binder, SmartSense Gen 2.0 compatible, fender mounts BB Standard: BSA, 68mm, Threaded Hanger Standard: UDH Tire Clearance: 48c Colors: Metallic Red; Chalk |
|---|---|
| Fork | Synapse Carbon, integrated crown race, 12x100mm thru-axle, flat mount disc, internal routing, 1-1/8" to 1-1/5" Delta steerer, 55mm offset, fender mounts |
| Bottom Bracket | Shimano BSA 68 |
| Headset | Integrated, 1-1/8" - 1-1/2" |
| Stem | Cannondale C1 Conceal, Alloy, 31.8, -6°: 80mm (44-48m), 90mm (51cm), 100mm (54-56cm), 110mm (58-61cm) |
| Handlebar | Vision Trimax Aero Alloy: 400mm (44-51cm), 420mm (54-61cm) |
| Saddle | Fizik Vento Argo X5, 140mm |
| Seatpost | Cannondale C1 Aero 27 Carbon, SmartSense compatible, 330mm length, 0mm offset (44-48cm), 15mm offset (51-61cm) Type: Rigid |
| Pedals | Not included |
| Grips | Cannondale Bar Tape, 3.5mm |
| Rear Derailleur | Shimano 105 Di2 7150 |
|---|---|
| Front Derailleur | Shimano 105 Di2 7150, braze-on |
| Crank | Shimano 105 7100, BSA, 50/34: 165mm (44cm), 170mm (48-51cm), 172.5 (54-56cm), 175mm (58-61) |
| Shifters | Shimano 105 Di2 R7170, wireless, 12-speed |
| Cassette | Shimano 105 7100, 11-34, 12-speed |
| Chain | Shimano 105 7100, 12-speed |
| Brakes | Shimano 105 7170 hydraulic disc, 160/160mm RT70 rotors Type: Shimano 105 Hydraulic Disc |
| Brake Levers | Shimano 105 Di2 7170 hydraulic disc |
| Rims | DT Swiss R470 DB, 28h |
|---|---|
| Spokes | Stainless Steel, 14g |
| Front Hub | Shimano RS470, 12x100mm centerlock |
| Rear Hub | Shimano RS470, 12x142mm centerlock |
| Tires | Vittoria Rubino Pro IV, 700x32c |
First added May 6
Last updated June 7